UVA Health looks at “COVID rebound” in patients who took Paxlovid

CHARLOTTESVILLE, Va. (WVIR) – COVID-19 case numbers are rising and for a few of these contaminated, it’s not their first time.

Some individuals are getting COVID-19 once more, simply days after they thought they had been within the clear. Docs say that is primarily occurring to sufferers who accomplished the drug Paxlovid. It’s Pfizer’s remedy advisable for sufferers who’re at the next well being danger, which might be both underlying situations or age.

“It could actually recommend that the virus is now replicating once more,” Dr. Costi Sifri with UVA Well being mentioned. “The frequency that happens and why it happens are the paramount questions proper now that we’re all investigating and positively what the CDC and you recognize, in Pfizer are looking at proper now.”

Docs are calling this, “COVID rebound.”

“Perhaps like someplace between like, day seven to day 12 every part will get worse once more. So that you get like these chilly and flu signs,” Dr. Invoice Petri with UVA Well being mentioned.

Although Dr. Petri says the research are ongoing about the reason for this form of rebound, they do have some speculations now.

“Is it that there’s form of a reservoir of a small quantity of virus that’s in a position to form of come again out after a remedy course? It’s possibly not sufficient to result in a optimistic antigen take a look at, it’s possibly sufficient that you just’re, you’re not transmissible, however it serves as a reservoir, after which after which comes again,” Dr. Sifri mentioned.

He says the drug remains to be about 90% efficient in stopping hospitalization for prime danger sufferers, after they have COVID-19.

“I’m carrying round in my again pocket that thought that it’s occurring most likely in a single to 10 to 1 in 20 individuals who full a course of Paxlovid,” Dr. Sifri mentioned.

He says Paxlovid remains to be a useful gizmo and it’s saving lives. He says because the sufferers have some immunity in them, they don’t seem to be prone to be hospitalized. Although, sufferers ought to nonetheless isolate in the event that they get COVID rebound to assist shield others.

Docs remind everybody to get vaccinated, keep updated with these boosters, and isolate in case you’re sick so we will restrict the extra extreme circumstances.

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