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Gene-edited dogs created from cloned skin cells for the first time


New gene-editing method might be used to get rid of disease-causing mutations from pedigree canine breeds and even from clones of particular person canines



Life



22 July 2022

Gene-edited beagle puppies

Okjae Koo/ToolGen

Two beagle canines have been born in South Korea from cloned pores and skin cells altered by CRISPR gene editing. CRISPR-edited canines have beforehand been created by altering fertilised eggs, however that is the primary time they’ve been created by cloning.

Many pure-bred pedigree canines have disease-causing mutations. Gene enhancing might be used to get rid of these with out affecting different traits. So, for this goal, the cloning method has benefits over the editing-eggs method, says Okjae Koo at biotech firm ToolGen.”[It] is extra dependable for producing varied pure-bred …



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