Gene-edited dogs created from cloned skin cells for the first time

New gene-editing method might be used to get rid of disease-causing mutations from pedigree canine breeds and even from clones of particular person canines
Life
22 July 2022
Gene-edited beagle puppies Okjae Koo/ToolGen
Two beagle canines have been born in South Korea from cloned pores and skin cells altered by CRISPR gene editing. CRISPR-edited canines have beforehand been created by altering fertilised eggs, however that is the primary time they’ve been created by cloning.
Many pure-bred pedigree canines have disease-causing mutations. Gene enhancing might be used to get rid of these with out affecting different traits. So, for this goal, the cloning method has benefits over the editing-eggs method, says Okjae Koo at biotech firm ToolGen.”[It] is extra dependable for producing varied pure-bred …